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Pharmacy, pharmaceutical sales, medical device sales and lending, poisonous and deleterious substances sales, etc.

Last Updated January 23, 2025

The contact point for each procedure is Health and Welfare Center Health Sanitation Division.
※The procedures for business operators of poisonous and deleterious substances, users of specific poisons, and researchers of specific poisons are handled by the Medical Care Bureau Medical Safety Division (045-671-3876).

(Notice)
In the procedures related to pharmaceutical affairs, the presentation and submission of the original certificate of qualification has been changed to presentation and submission of a copy.
In the procedures related to pharmaceutical affairs, the presentation of the original certificate of qualification (pharmacist's license, sales engagement certificate, course completion certificate, etc.) at the counter has been changed to presentation (submission) of a copy. In addition, the original certificate of qualification (diploma, etc.) has been changed to a copy. Be sure to check the original at the responsibility of the business operator who has obtained (acquired) permission. It is not necessary to state that the original has been certified on the copy presented and submitted.
Documents other than the certificate of qualification (certificate of family register (extract) book, registration certificate, medical certificate, etc.) remain the same as before.
For documents required for each procedure, please see the procedure guide posted in each industry section on this page.

Regarding the notification of the number of prescriptions handled, we have started accepting electronic applications on January 1, 2024!
About report of the number of handling prescriptions, we became able to report using Yokohama-shi electronic application, report system. All pharmacies in Yokohama are eligible. For details, please see the guide for users (PDF: 922KB).
In addition, we do not issue a “copy (duplicate)” of notification at the reception by electronic application. If you need a seal from the public health center, please use the paper-based procedure as before.

The law on ensuring the quality, efficacy and safety of pharmaceuticals and medical devices has been revised.
The conventional "officer performing business" has been abolished, and the name of "officer responsible for business related to pharmaceutical affairs" has been stated in the application form.
In the notification of change submitted on or after August 1, 2021, please state the name of the officer responsible for the business related to pharmaceutical affairs as of August 1, 2021 and the eligibility of the officer's disqualification clause.
However, this is not required if you have already submitted it in another notification of change or permission renewal application.
In addition, procedures under the Poisonous and Deleterious Substances Control Law remain unchanged.
(Reference)

Regarding the definition of "executives responsible for business related to pharmaceutical affairs" (PDF: 321KB)

Handling concerning the description of the name of “executives responsible for pharmaceutical affairs” in the application form for permission (Q & A) (PDF: 317KB)


seal is no longer required for applications related to pharmaceutical affairs.
[How to fill in]

  • The entry will be "Name only". (Names include prints, rubber stamps and stamps, as well as handwritten.)
  • Even if there is a mark on the form, you can use it as it is.
  • Even if seal is signed, there is no need to modify it.


※For individual consultation on procedures, please contact Health and Welfare Center Health Sanitation Division, the district governing the location of the pharmacy.

List of applications and notifications
Type of application and notificationOverviewApplication and Notification Procedures, etc.
Application for permissionWhen you start a new pharmacyApplication for permission to open Y01 pharmacy (WORD) (outside site)
Application for permission to open Y01 pharmacy (PDF) (outside site)
Notification of change
*Please pay attention to the timing of notification in the right column.
Exact: Notification items after the change
Advance: Matters to be reported before the change
Ex-postWhen the name of the establisher or Address (in the case of a corporation, the name or the location of the principal office) is changed

Notification of change of Y02 pharmacy (WORD) (outside site)
Notification of change of Y02 pharmacy (PDF) (outside site)
Notification of change of pharmacy (electronic application) [Target area: Nishi Ward, Konan Ward, Tsuzuki Ward  , Seya Ward] (outside site)

Ex-postIf the establisher is a corporation, the officer responsible for the business related to pharmaceutical affairs has been changed.
Ex-postWhen major parts of structural equipment are changed
Ex-postWhen the matters related to the shared use of the aseptic dispensing room are changed
Ex-postWhen normal business days and business hours are changed
Ex-postWhen the name of the administrator, Address or the number of working hours per week is changed.
Ex-postWhen the name of a pharmacist other than the administrator, registered seller, or the number of working hours per week is changed
Ex-postTypes of radiopharmaceuticals to be handled
Ex-postWhen the type of drug sales or other business performed at the pharmacy is changed.
Ex-postWhen the category of drugs to be sold or awarded is changed
AdvanceWhen changing the name of a pharmacy
AdvanceWhen changing the presence or absence of a pharmacist
AdvanceWhen changing Phone number or other contact information during consultation and emergency situations
AdvanceWhen changing the presence or absence of specific sales or other matters related to specific sales
AdvanceWhen changing the presence or absence of indication indicating that it is a health support pharmacy
Notification of the number of prescriptions handledWhen reporting the total number of prescriptions handled in the previous yearNotification of the number of prescriptions handled by Y04 pharmacies (outside site)
Notification of suspension, abolition, and resumptionWhen a pharmacy that has been abolished, suspended or suspended has been resumedNotification of suspension (abolition / reopening) of Y05 pharmacies / pharmaceutical sales business (outside site)
Application for renewalWhen continuing to obtain permission after the expiration of the validity periodApplication for license renewal of Y06 pharmacy establishment (outside site)
Application for renewal of permitWhen there is a change in the information on the permitApplication for rewriting grant of license of Y07 pharmacy, pharmaceutical sales business (outside site)
Application for Reissue of PermitWhen the permit is passed, broken, or lostApplication for reissuance of permit of Y08 pharmacy, pharmaceutical sales business (outside site)
Application for permission to concurrently serve as administratorsWhen an administrator takes office as a school pharmacistApplication for permission to concurrently serve as a Y09 pharmacy (store / sales office) manager (outside site)
Notification of abolition of concurrent post of managerWhen the administrator resigns from a school pharmacist, etc.Notification of abolition of concurrent post of Y10 pharmacy (store / sales office) manager (outside site)

※For individual consultation on procedures, please contact Health and Welfare Center Health Sanitation Division, which is responsible for the location of the store.

List of applications and notifications
Type of application and notificationOverviewApplication and Notification Procedures, etc.
Application for permissionWhen we start a new store sales businessApplication for permission to store sales of Y11 pharmaceuticals (WORD) (outside site)
Application for permission to store sales of Y11 pharmaceuticals (PDF) (outside site)
Notification of change
*Please pay attention to the timing of notification in the right column.
Exact: Notification items after the change
Advance: Matters to be reported before the change
Ex-postWhen the name of the business operator or Address (if it is a corporation, the name or the location of the principal office) is changed.

Notification of change in store sales business of Y12 pharmaceuticals (WORD) (outside site)
Notification of change in store sales business of Y12 pharmaceuticals (PDF) (outside site)
Notification of change in store sales of Y03 pharmaceuticals (electronic application) [Target areas: Nishi Ward, Konan Ward, Tsuzuki Ward  , Seya Ward] (outside site)

Ex-postWhen a business operator is a corporation, when an officer is responsible for business related to pharmaceutical affairs is changed.
Ex-postWhen major parts of structural equipment are changed
Ex-postWhen normal business days and business hours are changed
Ex-postWhen the name of the administrator, Address or the number of working hours per week is changed.
Ex-postWhen the name of a pharmacist or registered seller other than the administrator has been changed or the number of working hours per week
Ex-postWhen the type of sales or other business other than the store sales business is changed at the same store.
Ex-postWhen the category of drugs to be sold or awarded is changed
AdvanceWhen the name of a store is changed
AdvanceWhen changing Phone number or other contact information during consultation and emergency situations
AdvanceWhen changing the presence or absence of specific sales or other matters related to specific sales
Notification of suspension, abolition, and resumptionWhen a store that has been abolished, suspended or suspended has been resumedNotification of suspension (abolition / reopening) of Y05 pharmacies / pharmaceutical sales business (outside site)
Application for renewalWhen continuing to obtain permission after the expiration of the validity periodApplication for renewal of license for store sales of Y13 pharmaceuticals (outside site)
Application for renewal of permitWhen there is a change in the information on the permitApplication for rewriting grant of license of Y07 pharmacy, pharmaceutical sales business (outside site)
Application for Reissue of PermitWhen the permit is passed, broken, or lostApplication for reissuance of permit of Y08 pharmacy, pharmaceutical sales business (outside site)
Application for permission to concurrently serve as administratorsWhen an administrator takes office as a school pharmacistApplication for permission to concurrently serve as a Y09 pharmacy (store / sales office) manager (outside site)
Notification of abolition of concurrent post of managerWhen the administrator resigns from a school pharmacist, etc.Notification of abolition of concurrent post of Y10 pharmacy (store / sales office) manager (outside site)

※For individual consultation on procedures, please contact Health and Welfare Center Health Sanitation Division, which is responsible for your location.

List of applications and notifications
Type of application and notificationOverviewApplication and Notification Procedures, etc.
Application for permissionWhen starting a new wholesale sales businessApplication for permission from wholesale sales of Y14 pharmaceuticals (outside site)
Notification of changeWhen the name of the business operator or Address (if it is a corporation, the name or the location of the principal office) is changed.

Notification of change in wholesale sales of Y15 pharmaceuticals (outside site)
Notification of change in wholesale sales of Y03 pharmaceuticals (electronic application) [Target areas: Nishi Ward, Konan Ward, Tsuzuki Ward  , Seya Ward] (outside site)

When a business operator is a corporation, when an officer is responsible for business related to pharmaceutical affairs is changed.
When major parts of structural equipment are changed
When the name of the administrator or Address is changed
When the type of radiopharmaceutical to be handled is changed
When the type of drug sales or other business performed at the sales office is changed.
When the name of a sales office is changed
When Phone number or other contact information is changed during consultation and emergency situations
Notification of suspension, abolition, and resumptionWhen a business office that has been abolished, suspended or suspended has been resumedNotification of suspension (abolition / reopening) of Y05 pharmacies / pharmaceutical sales business (outside site)
Application for renewalWhen continuing to obtain permission after the expiration of the validity periodApplication for renewal of license for wholesale sales of Y16 pharmaceuticals (outside site)
Application for renewal of permitWhen there is a change in the information on the permitApplication for rewriting grant of license of Y07 pharmacy, pharmaceutical sales business (outside site)
Application for Reissue of PermitWhen the permit is passed, broken, or lostApplication for reissuance of permit of Y08 pharmacy, pharmaceutical sales business (outside site)
Application for permission to concurrently serve as administratorsWhen an administrator takes office as a school pharmacist
When the manager of sample wholesale or non-vitro diagnostic agent wholesale also serves as the manager of another sales office.
Application for permission to concurrently serve as a Y09 pharmacy (store / sales office) manager (outside site)
Notification of abolition of concurrent post of managerWhen the administrator resigns from a school pharmacist, etc.
When the manager of sample wholesale or non-vitro diagnostic agent wholesale no longer serves as the manager of another sales office.
Notification of abolition of concurrent post of Y10 pharmacy (store / sales office) manager (outside site)

※For individual consultation on procedures, please contact Health and Welfare Center Health Sanitation Division, which is responsible for your location.

List of applications and notifications
Type of application and notificationOverviewApplication and Notification Procedures, etc.
Application for permissionWhen starting a new sales or lending business for highly managed medical equipmentApplication for permission of sales and lending business of Y17 highly managed medical equipment (outside site)
Notification of changeWhen the name of the business operator or Address (if it is a corporation, the name or the location of the principal office) is changed.

Notification of change in Y18 medical device sales and lending business (outside site)
Y03 Notification of changes in the medical device sales and lending business (electronic application) [Applicable areas: Nishi Ward, Konan Ward, Tsuzuki Ward  , Seya Ward] (outside site)

When a business operator is a corporation, when an officer is responsible for business related to pharmaceutical affairs is changed.
When the type of business (selling or lending) is changed
When the name of the administrator or Address is changed
When the name of a sales office is changed
When major parts of structural equipment are changed
Notification of suspension, abolition, and resumptionWhen a business office that has been abolished, suspended or suspended has been resumedNotification of suspension (abolition / reopening) of Y05 pharmacies / pharmaceutical sales business (outside site)
Application for renewalWhen continuing to obtain permission after the expiration of the validity periodApplication for renewal of permission of sales and lending business of Y19 highly managed medical equipment (outside site)
Application for renewal of permitWhen there is a change in the information on the permitApplication for rewriting grant of license of Y07 pharmacy, pharmaceutical sales business (outside site)
Application for Reissue of PermitWhen the permit is passed, broken, or lostApplication for reissuance of permit of Y08 pharmacy, pharmaceutical sales business (outside site)
Application for permission to concurrently serve as administratorsWhen the manager concurrently serves as the manager of another sales officeApplication for permission to concurrently serve as a Y09 pharmacy (store / sales office) manager (outside site)
Notification of abolition of concurrent post of managerWhen the manager no longer serves as the manager of another sales office.Notification of abolition of concurrent post of Y10 pharmacy (store / sales office) manager (outside site)

※For individual consultation on procedures, please contact Health and Welfare Center Health Sanitation Division, which is responsible for your location.

List of applications and notifications
Type of application and notificationOverviewApplication and Notification Procedures, etc.
NotificationWhen starting a new management medical equipment sales business or lending businessNotification of sales and lending business of Y20 managed medical equipment (outside site)
Notification of changeWhen the name of the business operator or Address (if it is a corporation, the name or the location of the principal office) is changed.Notification of change in Y18 medical device sales and lending business (outside site)
When a business operator is a corporation, when an officer is responsible for business related to pharmaceutical affairs is changed.
When the name of the administrator or Address is changed
When the type of business (selling or lending) is changed
When the name of a sales office is changed
When the outline of structural equipment is changed
When other operations are changed
Manager registration formWhen a sales office that has notified the sales or lending business of medical equipment by March 31, 2005 reports the managerPlease use notification (outside site) of change of Y18 medical device sales business, loan business
Notification of suspension, abolition, and resumptionWhen a business office that has been abolished, suspended or suspended has been resumedNotification of suspension (abolition / reopening) of Y05 pharmacies / pharmaceutical sales business (outside site)

※For individual consultation on procedures, please contact Health and Welfare Center Health Sanitation Division, which is responsible for your location.

List of applications and notifications
Type of application and notificationOverviewApplication and Notification Procedures, etc.
Application for permissionWhen starting a new sales business for regenerative medicine, etc.Application for license of product sales business such as Y21 regenerative medicine (outside site)
Notification of changeWhen the name of the business operator or Address (if it is a corporation, the name or the location of the principal office) is changed.Y222 Notification of change in product sales business such as regenerative medicine (outside site)
When a business operator is a corporation, when an officer is responsible for business related to pharmaceutical affairs is changed.
When the name of the administrator or Address is changed
When the name of a sales office is changed
When major parts of structural equipment are changed
Notification of suspension, abolition, and resumptionWhen a business office that has been abolished, suspended or suspended has been resumedNotification of suspension (abolition / reopening) of Y05 pharmacies / pharmaceutical sales business (outside site)
Application for renewalWhen continuing to obtain permission after the expiration of the validity periodApplication for renewal of license of product sales business such as Y23 Regenerative Medicine (outside site)
Application for renewal of permitWhen there is a change in the information on the permitApplication for rewriting grant of license of Y07 pharmacy, pharmaceutical sales business (outside site)
Application for Reissue of PermitWhen the permit is passed, broken, or lostApplication for reissuance of permit of Y08 pharmacy, pharmaceutical sales business (outside site)

※For individual consultation on procedures, please contact Health and Welfare Center Health Sanitation Division, the district governing the location of the pharmacy.

List of applications and notifications
Type of application and notificationOverviewApplication and Notification Procedures, etc.
New establishmentWhen a new drug is manufactured and sold at a pharmacyApplication for manufacturing license of Y24 pharmacy manufacturing and sales pharmaceuticals (outside site)
Application for permission of manufacturing and sales business of Y25 pharmacy manufacturing and sales pharmaceuticals (outside site)
Notification of changeWhen the name of a pharmacy (manufacturing place, etc.) is changedY26 Notification of changes in manufacturing and sales and manufacturing industries of pharmacy manufacturing and sales pharmaceuticals (outside site)
When the name of the pharmacy establisher or Address (if it is a corporation, the name or the location of the main office) is changed
When the pharmacy establisher is a corporation, when the officer responsible for the business related to pharmaceutical affairs is changed.
When the name of the general manager of manufacturing and sales or the name of the manufacturing manager or Address is changed.
When major parts of structural equipment are changed
Production and sales approvalWhen manufacturing and selling an item that requires approval for manufacturing and salesApplication for manufacturing and sales approval of Y27 pharmacy manufacturing and sales pharmaceuticals (outside site)
Manufacturing and Sales NotificationWhen manufacturing and selling items that do not require approval for manufacturing and salesY28 Notification of manufacture and sale of pharmacy manufacturing and sales pharmaceuticals (outside site)
Notification of minor changes in manufacturing and sales approval itemsWhen the name of the pharmacy is changed due to the name change of the pharmacyNotification of minor change in manufacturing and sales approval items of Y29 pharmacy manufacturing and sales pharmaceuticals (outside site)
Notification of suspension, abolition, and resumptionWhen a pharmacy that has been abolished, suspended or suspended has been resumedNotification of suspension (abolition / reopening) of Y05 pharmacies / pharmaceutical sales business (outside site)
Application for renewalWhen continuing to obtain permission after the expiration of the validity periodApplication for renewal of license of manufacturing manufacturing of Y30 pharmacy manufacturing and sales pharmaceuticals (outside site)
Application for renewal of license of manufacturing and sales business of Y31 pharmacy manufacturing and sales pharmaceuticals (outside site)
Application for renewal of permitWhen there is a change in the information on the permitApplication for rewriting grant of license of Y07 pharmacy, pharmaceutical sales business (outside site)
Application for Reissue of PermitWhen the permit is passed, broken, or lostApplication for reissuance of permit of Y08 pharmacy, pharmaceutical sales business (outside site)
Notification of Approval ConsolidationPharmacy manufacturing and sales When the manufacture and sale of pharmaceuticals is no longer performed, when the manufacturing and sales business is abolished, or when the pharmacy is abolished.Notification of arrangement of manufacturing and sales approval of Y32 pharmacy manufacturing and sales pharmaceuticals (outside site)

※For individual consultation on procedures, please contact Health and Welfare Center Health Sanitation Division, which is responsible for the location of the store.

List of applications and notifications
Type of application and notificationOverviewApplication and Notification Procedures, etc.
Application for registrationWhen starting a new sale of poisonous or deleterious substancesD01 Application for registration of poisonous and deleterious substances sales business (outside site)
Notification of the establishment of a person in charge of handling poisonous and deleterious substancesWhen a store that handles the actual product has a person in charge of handling.D02 Notification of the establishment of a person in charge of handling poisonous and deleterious substances (poisonous and deleterious substances sales business) (outside site)
Notification of change in person responsible for handling poisonous and deleterious substancesWhen the person in charge of handling is changedD03 Notification of change in person in charge of handling poisonous and deleterious substances (poisonous and deleterious substances sales business) (outside site)
Notification of changeWhen the name of the business operator or the Address (in the case of a corporation, the name or main office) is changedD04 Notification of change in the poisonous and deleterious substance sales business (outside site)

When important parts of equipment (storage equipment, etc.) are changed

When the name of a store is changed
Notification of abolitionWhen we abolish sales at storesNotification of abolition of D05 poisonous and deleterious substance sales business (outside site)
Application for renewalIf you continue to register after the expiration of the validity periodD06 Application for renewal of registration of poisonous and deleterious substances sales business (external site)
Registration Form Renewal Grant ApplicationWhen there is a change in the information on the registration slipD07 Application for rewriting of registration slips for poisonous and deleterious substances sales business (outside site)
Application for re-issuance of registration formWhen the registration slip is over, broken, or lostD08 Application for reissuance of registration slip of poisonous and deleterious substances sales business (outside site)
Specific poisonous-owned items and quantity notificationWhen a specific poison was owned when the registration expiredD09 Notification of items and quantities of specified poisons (poisonous and deleterious substances sales business) (outside site)

※For consultation on procedures, please contact the Medical Care Bureau Medical Safety Division (045-671-3876).

List of applications and notifications
Type of application and notificationOverviewApplication and Notification Procedures, etc.
Notification・When conducting electric plating business using sodium cyanide or inorganic cyanide toxic substances and formulations containing them
・When conducting metal heat treatment business using sodium cyanide or inorganic cyanide toxic substances and formulations containing them
・When a container with a maximum loading capacity of 5,000 kg or more or a container with an internal volume specified in Article 13-13 (External Site) of the Ministry of Health, Labour and Welfare is loaded on a large vehicle to carry out transportation business.
・When conducting a project to control whiteness using sodium cyanide or arsenic compound poisons and preparations containing them
D51 Notification of business operators of poisonous and deleterious substances (outside site)
Notification of change in person responsible for handling poisonous and deleterious substancesWhen the person in charge of handling is changedD52 Notification of change in person in charge of handling poisonous and deleterious substances (business handler) (outside site)
Notification of changeWhen the name of the establisher or Address (in the case of a corporation, the name or the location of the principal office) is changedNotification of change in operator of D53 poisonous and deleterious substances (outside site)
When the item of poisonous or deleterious substances to be handled is changed
When the name of a business site is changed
When the location of a business site is changed
Notification of abolitionWhen the business is abolished, or when the notified poisonous or deleterious substance is no longer handled for business purposesD54 Notification of abolition of business operators of poisonous and deleterious substances (outside site)

※For consultation on procedures, please contact the Medical Care Bureau Medical Safety Division (045-671-3876).

List of applications and notifications
Type of application and notificationOverviewApplication and Notification Procedures, etc.
Designated application・When using a formulation containing salts of monofluall acetic acid to eliminate wild rats
・When a formulation containing aluminum phosphoride and its decomposition agent is used to control rats, insects, etc. in warehouses or containers.
Application for designation of D55 specific poisonous user (for those who run forests, etc.) (outside site)
Notification of change of application itemsWhen the name or Address (in the case of a corporation, the name or the location of the principal office) is changedNotification of change of designated application matter of D56 specific poison user (outside site)
When the person responsible for storing specific poisons is changed
When the storage location (storage equipment) of specific poisons is changed
When a part of the specified poisonous item to be used is abolished
Application for re-grantWhen a designated certificate is sent, broken, or lostApplication for reissuance of D57 Specific Poisonous User Designated Certificate (outside site)
Notification of abolition of businessWhen such business is abolishedD58 Notification of abolition of business by specific poisonous users (outside site)
Specific poisonous-owned items and quantity notificationWhen you own a specific poison when you are no longer a specific poison userD59 Notification of items owned and quantities of specified poisons (specified poison users) (outside site)

※For consultation on procedures, please contact the Medical Care Bureau Medical Safety Division (045-671-3876).

List of applications and notifications
Type of application and notificationOverviewApplication and Notification Procedures, etc.
Application for Permitting a Specific Poisonous ResearcherWhen manufacturing and using specified poisons for academic researchD60 Application for permission from specific poisonous researchers (external site)
Notification of changeWhen the name or Address is changedD61 Notification of changes in the application for permission of specific poisonous researchers (external site)
When the name of the research institute is changed
When the location of the Institute is changed
When a research item is changed
When an item of a specific poison is changed
When an important part of the equipment is changed
Notification of abolition of permission for specific poisonous researchersWhen the research is abolishedD62 Notification of abolition of permission for specific poisonous researchers (outside site)
Application for Renewal of Specific Poisonous Researcher PermitWhen there is a change in the information on the permitD63 Application for rewriting of Specific Poisonous Researcher Permit (outside site)
Application for Reissue of Specific Poisonous Researcher PermitWhen the permit is passed, broken, or lostD64 Application for reissuance of Specific Poisonous Researcher Permit (outside site)
Specific poisonous-owned items and quantity notificationWhen a specific poison was owned when the permission expiresD65 Notification of items and quantities of specified poisons (specified poisonous researchers) (external site)

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Inquiries to this page

Medical Care Bureau Health and Safety Department Medical Safety Division

Telephone: 045-671-3654

Telephone: 045-671-3654

Fax: 045-663-7327

Email address: ir-iryoanzen@city.yokohama.lg.jp

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Page ID: 495-140-017

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