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About Alzheimer's antiamyloid β antibody drug
Information on antibody drugs targeting Alzheimer's disease.
Last Updated December 24, 2024
About dementia
Dementia refers to a condition in which the brain changes due to various causes, cannot be done before, and has interfered with life.
There are various types of dementia depending on the causative disease, such as "Alzheimer's dementia", which is caused by the effects of the brain on nerve cells.
For more information, please visit the following page.
What is dementia?
In Alzheimer's disease, a protein called amyloid β (beta) in the brain for a long period of time causes the brain to gradually lose the function of nerve cells, and the brain to atrophy and overall decline. In recent years, the development of therapeutic agents targeting amyloid β has been progressing, and in Japan, "lecanemab" and "donanemab" have been approved.
About "Lecanemab" (Rekenbi® infusion)
In December 2023, domestic sales of lecanemab began. It is the first approved drug in Japan for people with mild dementia and MCI (mild cognitive impairment) due to Alzheimer's disease to control the progress of the disease itself by working on the causes of Alzheimer's disease.
To citizens who wish to do so
- Lecanemab is treated for those who have mild dementia due to Alzheimer's disease or those with mild cognitive impairment (MCI).
- Lecanemab is a drug that goes to the hospital once every two weeks and takes about an hour with infusion.
- Whether you can receive lecanemab treatment is based on the results of various tests (CDR (clinical dementia scale), MMSE (neuropsychological examination), amyloid PET examination or cerebrospinal fluid examination, etc.) at the medical institution that administers it. Judge. Depending on the results of the test, you may not be eligible for treatment if you wish.
- For treatment with lecanemab, first consult your doctor.
Procedures up to treatment
Flow diagram showing the procedure up to treatment
About dementia disease medical center, please see the following page.
Yokohama City Dementia Disease Medical Center
Medical institutions that can respond to the first dose of lecanemab (as of November 2024)
During the period from November 15 to November 29, 2024, we conducted a questionnaire survey of all hospitals and some clinics in the city and conducted initial administration facilities. ※There were 19 medical institutions that responded that they could respond.
※What is the first administration facility? It is a medical institution that meets requirements such as the placement of doctors and response to side effects. For details, please refer to the “Guidelines for Promotion of Optimal Use (Recanemab)” on the website of the Ministry of Health, Labour and Welfare below. About Lecanemab (Rekenbi R infusion) (Ministry of Health, Labour and Welfare website) (outside site)
Of these, 17 medical institutions that have accepted new patients and have agreed to the publication on the Motoichi HP are as follows.
[Notes]
- For treatment of lecanemab, etc., first consult your GP.
- If you wish to visit the following medical institutions, please contact the listed Phone number in advance and check the "Request for Consultation" on the right column.
Name of medical institution | Address | Phone number | Request for consultation |
|---|---|---|---|
Social Welfare Corporation | 3-6-1, Shimosueyoshi, Tsurumi-ku | 045-576-3000 | The letter of introduction is not required, but it is desirable to have it. The Memory Clinic, an outpatient specializing in dementia, requires a letter of introduction and requires advance reservations. If you are in a hurry, you can receive a letter of introduction at the first visit (Shoshin) outpatient clinic on water and Thursday without a letter of introduction. |
| Yokohama Municipal Citizen's Hospital | 1-1 Mitsuzawa Nishi, Kanagawa-ku, 1-1 | 045-316-4580 | A letter of introduction or medical information report is required. |
Kanagawa Prefectural Police Tomokai | 3-7-3, Minatomirai, Nishi-ku | 045-221-8181 | A letter of introduction or medical information report is required. Advance reservations are required. |
| Yokohama City Minato Red Cross Hospital | 3-12-1, Shinyamashita, Naka-ku | 045-628-6761 | A letter of introduction or medical information report is required. Advance reservations are required. |
Public university corporation Yokohama City University | 4-57, Urafunecho, Minami-ku | 045-261-5656 | A letter of introduction or medical information report is required. Advance reservations are required. |
Medical corporation Nimeikai | 2-10-36, Kaminagaya, Kounan-ku | 045-846-1001 | A letter of introduction or medical information report is required. Advance reservations are required. |
Social Welfare Corporation | 3-2-10, Kounandai, Kounan-ku | 045-832-1111 | Advance reservations are required. |
Yokohama City Apolexy and Spinal Nerves Center | 1-2-1, Takigashira, Isogo-ku | 045-753-2500 | You can have a medical examination without a letter of introduction or appointment, but it will take selected medical expenses and waiting time. In addition, in order to treat more patients, we ask for infusion at cooperating clinics after 6 months after the first administration. |
Public university corporation | 3-9, Fukuura, Kanazawa-ku | 045-787-2800 | A letter of introduction or medical information report is required. Advance reservations are required. |
Federation of National Public Service Mutual Aid Associations | 1-21-1, Mutsuurahigashi, Kanazawa-ku | 045-782-2101 | A letter of introduction or medical information report is required. |
Workers' Health and Safety Organization | 3211, Kozukuecho, Kouhoku-ku | 045-474-8882 | A letter of introduction or medical information report is required. Advance reservations are required. |
| Showa University Fujigaoka Hospital | 1-30, Fujigaoka, Aoba-ku | 045-971-1151 | A letter of introduction or medical information report is required. |
Medical corporation Meiyoshikai | 433, Edacho, Aoba-ku | 045-911-2011 | A letter of introduction or medical information report is required. Advance reservations are required. |
Medical Corporation Green Society | 2201-5, Kuroganecho, Aoba-ku | 045-903-7106 | You can consult without a letter of introduction or reservation. |
| Showa University Northern Yokohama Hospital | 35-1, Chigasakichuo, Tsuzuki-ku | 045-949-7000 | A letter of introduction or medical information report is required. Advance reservations are required. You must not have severe dementia. |
National Hospital Organization | 3-60-2, Harajuku, Totsuka-ku | 045-853-8357 | A letter of introduction or medical information report is required. Advance reservations are required. |
Medical Corporation Yokohama Future Healthcare System | 1-40-34, Izumichuokita, Izumi-ku | 045-800-0320 |
Inquiries to this page
Medical Policy Division, Medical Care Bureau Medical Policy Department
Telephone: 045-671-2466
Telephone: 045-671-2466
Fax: 045-664-3851
Email address: ir-seisaku@city.yokohama.lg.jp
Page ID: 508-921-077
